Invention Grant
- Patent Title: 2-amino-3-fluoro-3-(fluoromethyl)-6-methyl-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors
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Application No.: US15233463Application Date: 2016-08-10
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Publication No.: US10011596B2Publication Date: 2018-07-03
- Inventor: Karsten Juhl , Lena Tagmose , Mauro Marigo
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: DK201500465 20150812
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07B59/00 ; C07D211/72 ; C07D401/12 ; C07D413/12 ; C07D211/76
Abstract:
The present invention provides compounds of Formula I for the treatment of neurodegenerative or cognitive diseases. The method further provides for piperidine-2-one and piperidine-2-thione intermediates to compounds of formula I.
Public/Granted literature
- US20170044151A1 2-Amino-3-Fluoro-3-(Fluoromethyl)-6-Methyl-6-Phenyl-3,4,5,6-Tetrahydropyridines as BACE1 Inhibitors Public/Granted day:2017-02-16
Information query
