An imaging system includes a computed tomography (CT) acquisition unit and at least one processor. The CT acquisition unit includes an X-ray source and a CT detector configured to collect CT imaging data of an object. The at least one processor is operably coupled to the CT acquisition unit, and configured to reconstruct an initial image using the CT imaging information, the initial image including at least one object representation portion and at least one artifact portion; identify at least one region of the initial image containing at least one artifact and isolate the at least one artifact by analyzing the initial image using an artifact dictionary and a non-artifact dictionary, the artifact dictionary including entries describing corresponding artifact image portions, the non-artifact dictionary including entries defining corresponding non-artifact image portions; and remove the at least one artifact from the initial image to provide a corrected image.