The present disclosure relates to the field of communication technology, and provides a data transmission method, a data reception and detection method, a base station and a UE on the basis of a non-orthogonal mode. Before the transmission of pieces of data on physical resources by the base station, a plurality of pieces of data is firstly mapped to the physical resources at an amount not greater than the number of the pieces of data, each piece of data in the plurality of pieces of data is mapped to at least one physical resource, and the number of the physical resources to which each piece of data is mapped is not completely the same. Then, the pieces of data on the physical resources are transmitted by the base station. According to the present disclosure, it is able to transmit more pieces of data through fewer physical resources, thereby to improve the data transmission capability for the communication system.