Invention Grant
- Patent Title: Pyrrolidine amide compounds as histone demethylase inhibitors
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Application No.: US15482584Application Date: 2017-04-07
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Publication No.: US10022354B2Publication Date: 2018-07-17
- Inventor: Kwong Wah Lai , Jun Liang , Birong Zhang , Sharada Labadie , Daniel Ortwine , Peter Dragovich , James Kiefer , Victor S. Gehling , Jean-Christophe Harmange
- Applicant: GENENTECH, INC. , CONSTELLATION PHARMACEUTICALS, INC.
- Applicant Address: US CA South San Francisco US MA Cambridge
- Assignee: GENENTECH, INC.,CONSTELLATION PHARMACEUTICALS INC.
- Current Assignee: GENENTECH, INC.,CONSTELLATION PHARMACEUTICALS INC.
- Current Assignee Address: US CA South San Francisco US MA Cambridge
- Agency: Viksnins Harris Padys Malen LLP
- Priority: WOPCT/CN2014/088309 20141010
- Main IPC: C07D237/04
- IPC: C07D237/04 ; A61K31/41 ; A61K31/4025 ; C07D207/04
Abstract:
The present invention relates to compounds useful as inhibitors of one or more histone demethylases, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Public/Granted literature
- US20170312252A1 PYRROLIDINE AMIDE COMPOUNDS AS HISTONE DEMETHYLASE INHIBITORS Public/Granted day:2017-11-02
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