发明授权
- 专利标题： N,N′ substituted piperidinamine compounds, and preparation method and usage thereof
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申请号： US15105702申请日： 2014-12-19
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公开(公告)号： US10023565B2公开(公告)日： 2018-07-17
- 发明人: Wu Zhong , Song Li , Yanqun Zeng , Junhai Xiao , Xinbo Zhou , Zhibing Zheng , Xingzhou Li , Xiaokui Wang , Lili Wang
- 申请人： Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
- 申请人地址： CN Beijing
- 专利权人： INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA
- 当前专利权人： INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA
- 当前专利权人地址： CN Beijing
- 代理机构： Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 优先权： CN201310704759 20131220
- 国际申请： PCT/CN2014/094338 WO 20141219
- 国际公布： WO2015/090226 WO 20150625
- 主分类号： A61K31/454
- IPC分类号： A61K31/454 ; A61K31/506 ; C07D401/04 ; C07D417/06 ; A61K45/06
摘要：
The present invention relates to a compound of formula (I), a stereomeride, pharmaceutically acceptable salt, a solvate or an N-oxide thereof, a medicine composition comprising the compound, a method for preparing the compound, and a usage of the compound in treating diseases related to Hsp70. The diseases are preferably selected from tumors, neurodegenerative diseases, and allogeneic transplantation rejection and infection.
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