- 专利标题: 19-nor neuroactive steroids and methods of use thereof
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申请号: US15273125申请日: 2016-09-22
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公开(公告)号: US10023606B2公开(公告)日: 2018-07-17
- 发明人: Gabriel Martinez Botella , Boyd L. Harrison , Albert Jean Robichaud , Francesco G. Salituro , Richard Thomas Beresis
- 申请人: SAGE THERAPEUTICS, INC.
- 申请人地址: US MA Cambridge
- 专利权人: Sage Therapeutics, Inc.
- 当前专利权人: Sage Therapeutics, Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Goodwin Procter LLP
- 优先权: WOPCT/CN2013/074319 20130417
- 主分类号: C07J43/00
- IPC分类号: C07J43/00
摘要:
Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, tinnitus, status epilepticus.
公开/授权文献
- US20170233432A1 19-NOR NEUROACTIVE STEROIDS AND METHODS OF USE THEREOF 公开/授权日:2017-08-17
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