- 专利标题: Methods for treating occular irritation involving tearing by administering modulators of TRPM8
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申请号: US15350938申请日: 2016-11-14
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公开(公告)号: US10028920B2公开(公告)日: 2018-07-24
- 发明人: Carlos Belmonte Martínez , Juana Gallar Martínez , Antonio Ferrer Montiel , Asia Fernández Carvajal , Félix Viana De La Iglesia
- 申请人: UNIVERSIDAD MIGUEL HERNÁNDEZ DE ELCHE , CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS C.S.I.C.
- 申请人地址: ES Elche ES Madrid
- 专利权人: UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE,CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFÍCAS C.S.I.C.
- 当前专利权人: UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE,CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFÍCAS C.S.I.C.
- 当前专利权人地址: ES Elche ES Madrid
- 代理机构: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 优先权: ES201031341 20100908
- 主分类号: A61K31/045
- IPC分类号: A61K31/045 ; A61K45/06 ; A61K31/00 ; A61K31/047 ; A61K31/075 ; A61K31/16 ; A61K31/164 ; A61K31/167 ; A61K31/17 ; A61K31/196 ; A61K31/215 ; A61K31/22 ; A61K31/221 ; A61K31/245 ; A61K31/27 ; A61K31/352 ; A61K31/357 ; A61K31/381 ; A61K31/4025 ; A61K31/4164 ; A61K31/4745 ; A61K31/496 ; A61K31/505 ; A61K31/55 ; A61K31/662 ; A61K31/7105 ; A61K31/713 ; A61K45/00 ; A61K9/00 ; A61K31/07 ; A61K31/4178 ; A61K38/13
摘要:
The invention relates to therapeutic compositions for the treatment of dry eye, more specifically to compositions comprising a TRPM8 receptor agonist ligand. Furthermore, the invention relates to therapeutic compositions for the treatment of epiphora, more specifically to compositions comprising a TRPM8 receptor antagonist.
公开/授权文献
- US20170071875A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DRY EYE 公开/授权日:2017-03-16
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