- 专利标题： Method of producing myeloid blood cells
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申请号： US13825883申请日： 2011-09-28
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公开(公告)号： US10034900B2公开(公告)日： 2018-07-31
- 发明人: Satoru Senju
- 申请人： Satoru Senju
- 申请人地址： JP Kumamoto
- 专利权人： NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY
- 当前专利权人： NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY
- 当前专利权人地址： JP Kumamoto
- 代理机构： Greenblum & Bernstein, P.L.C.
- 优先权： JP2010-221809 20100930
- 国际申请： PCT/JP2011/072234 WO 20110928
- 国际公布： WO2012/043651 WO 20120405
- 主分类号： A61K35/14
- IPC分类号： A61K35/14 ; C12N15/85 ; A61K35/15 ; C12N5/0784 ; C12N5/0786
摘要：
An object of the present invention is to provide a method of producing a myeloid blood cell possessing a proliferative capability. According to the present invention, provided is a method of producing a myeloid blood cell possessing a proliferative capability, including forcedly expressing (A) a cMYC gene, and (B) at least one gene selected from the group consisting of a BMI1 gene, an EZH2 gene, an MDM2 gene, an MDM4 gene, and an HIF1A gene in a myeloid blood cell.
公开/授权文献
- US20130195818A1 METHOD OF PRODUCING MYELOID BLOOD CELLS 公开/授权日：2013-08-01
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