Invention Grant
- Patent Title: PRMT1 inhibitors and uses thereof
-
Application No.: US15231651Application Date: 2016-08-08
-
Publication No.: US10039748B2Publication Date: 2018-08-07
- Inventor: Lorna Helen Mitchell , Gideon Shapiro , Richard Chesworth , Paula Ann Boriack-Sjodin , Oscar Miguel Moradei , Kevin Wayne Kuntz
- Applicant: Epizyme, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Epizyme, Inc.
- Current Assignee: Epizyme, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K31/4155
- IPC: A61K31/4155
Abstract:
Described herein are compounds of Formula (I-a) and (I-b), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.
Public/Granted literature
- US20170182005A1 PRMT1 INHIBITORS AND USES THEREOF Public/Granted day:2017-06-29
Information query
IPC分类:
