Invention Grant
- Patent Title: 2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors
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Application No.: US15524546Application Date: 2015-11-09
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Publication No.: US10045974B2Publication Date: 2018-08-14
- Inventor: Karsten Juhl , Lena Tagmose , Mauro Marigo
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: DK201400648 20141110; DK201500447 20150807
- International Application: PCT/EP2015/076015 WO 20151109
- International Announcement: WO2016/075063 WO 20160519
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/4439 ; C07D417/12 ; C07D413/12
Abstract:
The present invention is directed to compounds of formula (I) which are inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for which the reduction of Aβ deposits is beneficial such as Alzheimer's disease.
Public/Granted literature
- US20170319564A1 2-Amino-6-(Difluoromethyl)-5,5-Difluoro-6-Phenyl-3,4,5,6-Tetrahydropyridines as BACE1 Inhibitors Public/Granted day:2017-11-09
Information query
