Invention Grant
- Patent Title: Optical resolution method of lenalidomide
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Application No.: US15312788Application Date: 2015-05-21
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Publication No.: US10047068B2Publication Date: 2018-08-14
- Inventor: Yosuke Tojo , Masashi Mita , Wolfgang Lindner
- Applicant: Shiseido Company, Ltd
- Applicant Address: JP Tokyo
- Assignee: Shiseido Company, Ltd.
- Current Assignee: Shiseido Company, Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Priority: JP2014-106388 20140522
- International Application: PCT/JP2015/064643 WO 20150521
- International Announcement: WO2015/178461 WO 20151126
- Main IPC: C07D401/04
- IPC: C07D401/04
Abstract:
The problem addressed by the present invention is to provide a novel method for separating and purifying pure enantiomer of lenalidomide. Pure enantiomer of lenalidomide can be separated and purified by using, as the mobile phase, an organic solvent selected from the group consisting of aprotic solvents, secondary alcohols, and mixtures thereof.
Public/Granted literature
- US20170190686A1 OPTICAL RESOLUTION METHOD OF LENALIDOMIDE Public/Granted day:2017-07-06
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