Disclosed is an embedding cassette for biopsy to embed tissue received in an embedding mold provided with a space to receive the tissue when the embedding cassette is combined with the embedding mold, including a body provided with a space communicating with the receipt space of the combined embedding mold so that an injected paraffin solution may coagulate therein during embedding of the tissue and at least one paraffin barrier groove formed at the edge of the lower surface of the body, and, when the embedding cassette is combined with the embedding mold and embedding of the tissue is carried out, the injected paraffin solution flows into the at least one paraffin barrier groove and forms a barrier and, thereby, leakage of the paraffin solution between the embedding cassette and embedding mold is prevented.