Invention Grant
- Patent Title: Histone deacetylase inhibitors and compositions and methods of use thereof
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Application No.: US15315713Application Date: 2015-06-01
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Publication No.: US10065948B2Publication Date: 2018-09-04
- Inventor: Celia Dominguez , Ignacio Muñoz-Sanjuán , Roland W. Bürli , Christopher A. Luckhurst , Daniel R. Allen , Gilles Raphy , Perla Breccia , Alan F. Haughan , Grant Wishart , Samantha J. Hughes , Rebecca E. Jarvis , Huw D. Vater , Stephen D. Penrose , Michael Wall , Andrew J. Stott , Elizabeth A. Saville-Stones
- Applicant: CHDI Foundation, Inc.
- Applicant Address: US NY New York
- Assignee: CHDI Foundation, Inc.
- Current Assignee: CHDI Foundation, Inc.
- Current Assignee Address: US NY New York
- Agency: Sheppard Mullin Richter & Hampton LLP
- International Application: PCT/US2015/033511 WO 20150601
- International Announcement: WO2015/187542 WO 20151210
- Main IPC: C07D417/04
- IPC: C07D417/04 ; C07D231/54 ; C07D401/04 ; C07D403/04 ; C07D231/56 ; C07D239/88 ; C07D277/60 ; C07D239/70 ; C07C259/08

Abstract:
Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.
Public/Granted literature
- US20170101402A1 HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF Public/Granted day:2017-04-13
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