The embodiments of the present invention relates to a signal processing method and a base station. The method includes: splitting, by a base station, an array antenna to form a first transmit beam and a second transmit beam in a downlink direction, where the first transmit beam covers a first cell and the second transmit beam covers a second cell; performing, by the base station, weighting on the array antenna in an uplink direction to form a receive beam; and transmitting, by the base station, a downlink signal to first user equipment UE by using the first transmit beam, and performing uplink signal transmission with the first UE by using the receive beam, where the first UE is located in the first cell.