Invention Grant
- Patent Title: Tissue interface augmentation device for ligament/tendon reconstruction
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Application No.: US14905169Application Date: 2014-07-21
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Publication No.: US10080644B2Publication Date: 2018-09-25
- Inventor: Cho Hong James Goh , Kok Hiong Thomas Teh , Pujiang Shi , Hoi Po James Hui , Jun Li
- Applicant: National University of Singapore , Agency for Science, Technology and Research
- Applicant Address: SG Singapore SG Singapore
- Assignee: National University of Singapore,Agency for Science, Technology and Research
- Current Assignee: National University of Singapore,Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore SG Singapore
- Agency: Crockett & Crockett, PC
- Agent K. David Crockett, Esq.; Niky Economy Syrengelas, Esq.
- Priority: SG201305559-5 20130719
- International Application: PCT/SG2014/000345 WO 20140721
- International Announcement: WO2015/009246 WO 20150122
- Main IPC: A61F2/08
- IPC: A61F2/08 ; A61L27/36 ; A61L27/38 ; A61L27/46 ; A61L27/48 ; A61L27/54 ; A61L27/56

Abstract:
The present invention relates to a device for the interfacial augmentation of tissue grafts for the purpose of tendon and ligament reconstruction. The inventive device works both as a delivery vessel for osteoconductive and osteoinductive factors and as a scaffold to stimulate and support bone ingrowth and comprises a tubular composite silk sheath, said tubular composite silk sheath comprising: a backbone consisting of a tubular silk mesh, and a carrier material consisting of a porous silk sponge, wherein said tubular silk mesh consists of degummed silk fibroin fibers, wherein said porous silk sponge comprises silk fibroin fibers and hydroxyapatite particles and said tubular silk mesh and said porous silk sponge form a composite material. The present invention is also directed to a method for the manufacturing of such augmentation devices, a method for fixation of the thus fabricated tissue interface augmentation devices onto ligament or tendon grafts, a method for applying such devices for ligament and/or tendon reconstruction to tendon grafts, as well as their application in ligament and tendon reconstruction.
Public/Granted literature
- US20160157992A1 TISSUE INTERFACE AUGMENTATION DEVICE FOR LIGAMENT/TENDON RECONSTRUCTION Public/Granted day:2016-06-09
Information query
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