In one embodiment, a system may include a gas turbine system. the gas turbine system includes a gas turbine, an after-treatment system that may receive exhaust gases from the gas turbine system, and a controller that may receive inputs and model operational behavior of an industrial plant based on the inputs. The industrial plant may include the gas turbine and the after-treatment system. The controller may also determine one or more operational parameter setpoints for the industrial plant, select the one or more operational parameter setpoints that reduce an output of a cost function, and apply the one or more operational parameter setpoints to control the industrial plant.