Invention Grant
- Patent Title: Multicyclic compounds and methods of use thereof
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Application No.: US14950834Application Date: 2015-11-24
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Publication No.: US10085968B2Publication Date: 2018-10-02
- Inventor: Liming Shao , John Emmerson Campbell , Michael Charles Hewitt , Una Campbell , Taleen G. Hanania
- Applicant: Sunovion Pharmaceuticals, Inc. , PGI Drug Discovery LLC
- Applicant Address: US MA Marlborough US NY Tarrytown
- Assignee: Sunovion Pharmaceuticals Inc.,PGI Drug Discovery LLC.
- Current Assignee: Sunovion Pharmaceuticals Inc.,PGI Drug Discovery LLC.
- Current Assignee Address: US MA Marlborough US NY Tarrytown
- Agency: Heslin, Rothenberg, Farley & Mesiti P.C.
- Main IPC: C07D233/00
- IPC: C07D233/00 ; C07D403/02 ; C07D403/14 ; C07D231/00 ; C07D487/02 ; C07D487/00 ; C07D405/00 ; C07D409/00 ; C07D495/02 ; A61K31/415 ; A61K31/40 ; C07D277/22 ; A61K31/381 ; C07D277/60 ; C07D333/54 ; C07D333/76 ; C07D333/78 ; C07D495/04 ; C07D495/20 ; A61K31/435 ; A61K31/55 ; A61K45/06

Abstract:
Provided herein are multicyclic compounds of formula (IVa), shown below, wherein R1, R2, R3, R4, R5, R6, R7, m, and n are defined herein elsewhere, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.
Public/Granted literature
- US20160083399A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF Public/Granted day:2016-03-24
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