The present application discloses an intelligent flexible hub powder spraying line and process. The intelligent flexible hub powder spraying line comprises a control system, a wheel type recognition system, a brace recognition system, a conveying chain, off-line carrying robots, a powder spraying isolation area, an oven, an on-line area, an off-line area and accessory equipment, wherein the conveying chain comprises a chain, braces and a driving mechanism. By applying a plurality of powder spraying units and the recognition systems, multiple kinds of powder can be simultaneously sprayed with different parameters.