A disinfestation sheet includes a carrier layer with a first and second surface with active pesticidal particles formed therein. The active pesticidal particles contain pesticidal ingredients selected from pyrethroid family or the like. The carrier layer has channels formed therein. The channels form one or more paths between one or more pesticidal particles and at least one of the first and the second surfaces to allow diffusion of the active pesticidal ingredient from the pesticidal particles to at least one of the first and the second surfaces of the carrier layer. The disinfestation sheet may further comprise antioxidant compounds. The disinfestation sheet may also have a base layer attached to the second surface of the carrier layer, an adhesive grip layer attached to the base layer and a support layer attached to the grip layer, where in the support layer is detachable. The carrier layer may also comprise ridges extending outwardly from the second surface. A method of manufacturing a disinfestation sheet comprising the mixing and blow-extrusion of pesticidal and polymer pellets is also defined.