Invention Grant
- Patent Title: Reagent for gene-drug therapeutics
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Application No.: US14439330Application Date: 2013-10-29
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Publication No.: US10100331B2Publication Date: 2018-10-16
- Inventor: Heng-Phon Too , Yoon Khei Ho , Lihan Zhou
- Applicant: Agency for Science, Technology and Research , National University of Singapore
- Applicant Address: SG Singapore
- Assignee: Agency for Science, Technology and Research
- Current Assignee: Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore
- Agency: Schwegman Lundberg & Woessner, P.A.
- International Application: PCT/SG2013/000464 WO 20131029
- International Announcement: WO2014/070111 WO 20140508
- Main IPC: C12N15/87
- IPC: C12N15/87 ; C12N15/85 ; C12N5/00 ; A61K31/7084 ; A61K48/00 ; A61K31/711 ; A61K47/34 ; A61K9/127 ; A61K39/00

Abstract:
The present invention relates to a composition for transfecting a cell with a genetic material comprising a first agent capable of directing the genetic material away from the acidic compartments in the cell and a second agent capable of stabilizing the microtubule or a network thereof. The invention also relates to the use of the composition in the manufacture of a medicament for treating a disease, a method for delivering a genetic material into a cell and a kit.
Public/Granted literature
- US20150361449A1 NOVEL REAGENT FOR GENE-DRUG THERAPEUTICS Public/Granted day:2015-12-17
Information query
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