For example, a wireless station may be configured to generate a plurality of time-domain streams in a time domain, the plurality of time-domain streams comprising at least a first time-domain stream comprising a first data sequence in a first interval and a second time-domain stream comprising a second data sequence in the first interval, the first time-domain stream comprises a time-inverted and sign-inverted complex conjugate of the second data sequence in a second interval subsequent to the first interval, and the second time-domain stream comprises a time-inverted complex conjugate of the first data sequence in the second interval; to convert the plurality of time-domain streams into a respective plurality of frequency-domain streams in a frequency domain; and to transmit a Multiple-Input-Multiple-Output (MIMO) transmission based on the plurality of frequency-domain streams.