A system that incorporates the subject disclosure may include, for example, determining an interference based on a channel gain for each signal of a group of signals received at a receiver from a group of transmitters. A determination is made of an interference value based on a group of interference signals received at a receiver from a group of transmitters, wherein the interference value is based on channel gains that are estimated for the group of transmitters, and wherein a portion of the interference is self-interference generated from transmitting and receiving at a same time. One of an analog time domain cancellation, a digital time domain cancellation or both, is performed responsive to a determination that the interference value does not satisfy a threshold range of an analog-to-digital converter of the receiver. Other embodiments are disclosed.