System and method can support data communication in a heterogeneous environment. The system can establish a connection between a first device and a second device, wherein the connection is based on a protocol, which associates a host mode or an accessory mode with one or more connected devices. Furthermore, a controller on the first device can determine a device type associated with the second device, and can configure the first device to be in either the host mode or the accessory mode, based on the determined device type associated with the second device, to handle data communication between the first device and the second device.