- 专利标题： Methods for reducing corneal nerves damage, corneal lymphangiogenesis or immunity to corneal antigens in dry-eye associated ocular surface diseases by IL-1Ra
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申请号： US12685510申请日： 2010-01-11
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公开(公告)号： US10117906B2公开(公告)日： 2018-11-06
- 发明人: Reza Dana , Mohammad Dastjerdi , Sunil Chauhan
- 申请人： Reza Dana , Mohammad Dastjerdi , Sunil Chauhan
- 申请人地址： US MA Boston
- 专利权人： The Schepens Eye Research Institute, Inc.
- 当前专利权人： The Schepens Eye Research Institute, Inc.
- 当前专利权人地址： US MA Boston
- 代理机构： Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- 代理商 Ingrid A. Beattie
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K49/00 ; A61B5/00 ; A61K38/19 ; A61K38/20 ; A61K38/17 ; A61K9/00 ; C12N15/113
摘要：
The invention provides methods and compositions for minimizing, preventing, or treating damage to corneal nerves by administering to a subject with such damage or at risk of exposure to such damage a composition which blocks an activity of an IL-1 cytokine and/or an IL-17 cytokine.
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