Invention Grant
- Patent Title: Tricyclic DLK inhibitors and uses thereof
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Application No.: US15699095Application Date: 2017-09-08
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Publication No.: US10131675B2Publication Date: 2018-11-20
- Inventor: Anthony Estrada , Snahel Patel , Terry Kellar , Malcolm Huestis , Daniel Shore , Michael Siu
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Jonathan Duffield
- Main IPC: C07D498/14
- IPC: C07D498/14 ; C07D491/14 ; C07D519/00 ; A61K31/5383 ; A61K45/06 ; A61K31/553

Abstract:
The invention relates to compounds of formula (I) and salts thereof: wherein ring A and R1-R2 have any of the values defined in the specification. The compounds and salts are useful for treating DLK mediated disorders. The invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable salt thereof, as well as methods of using said compounds, salts, or compositions as DLK inhibitors and for treating neurodegeneration diseases and disorders.
Public/Granted literature
- US20170369510A1 TRICYCLIC DLK INHIBITORS AND USES THEREOF Public/Granted day:2017-12-28
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