- 专利标题: Peptide compositions having 4 linked CTL epitopes and uses thereof
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申请号: US15030678申请日: 2014-10-20
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公开(公告)号: US10137183B2公开(公告)日: 2018-11-27
- 发明人: Satoshi Fukaya , Toshihiro Osada , Hiroshi Wada
- 申请人: TAIHO PHARMACEUTICAL CO., LTD.
- 申请人地址: JP Tokyo
- 专利权人: Taiho Pharmaceutical Co., Ltd.
- 当前专利权人: Taiho Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Foley & Lardner LLP
- 优先权: JP2013-218524 20131021; JP2014-155132 20140730
- 国际申请: PCT/JP2014/077807 WO 20141020
- 国际公布: WO2015/060235 WO 20150430
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K14/00 ; C07K14/82 ; C07K14/74 ; C07K14/47
摘要:
This invention provides a cancer antigen peptide that can be administered to a wide range of cancer patients in the form of a peptide vaccine for cancer without the need for HLA typing and regardless of the HLA types of patients. Such peptide having 4 linked CTL epitopes is obtained by linking 4 CTL epitope peptides selected from among CTL epitope peptides derived from tumor antigen molecules that are reported to have the capacity for CTL induction via linkers.
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