发明授权
- 专利标题： Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication
-
申请号： US15749158申请日： 2016-08-10
-
公开(公告)号： US10138253B2公开(公告)日： 2018-11-27
- 发明人: John F. Kadow , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Zhongyu Wang
- 申请人： ViiV Healthcare UK (No.5) Limited
- 申请人地址： GB Brentford, Middlesex
- 专利权人： ViiV HEALTHCARE UK (NO.5) LIMITED
- 当前专利权人： ViiV HEALTHCARE UK (NO.5) LIMITED
- 当前专利权人地址： GB Brentford, Middlesex
- 代理商 Robert H. Brink; Edward R. Gimmi; William R. Majarian
- 国际申请： PCT/IB2016/054827 WO 20160810
- 国际公布： WO2017/025913 WO 20170216
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D498/22 ; A61K31/437 ; C07D498/16 ; C07D498/06 ; A61P31/18 ; A61K31/4985
摘要：
Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.