Invention Grant
- Patent Title: Isoxazole analogs as FXR agonists and methods of use thereof
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Application No.: US15597417Application Date: 2017-05-17
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Publication No.: US10144729B2Publication Date: 2018-12-04
- Inventor: Yat Sun Or , Jun Ma , Bin Wang , Yong He , Xuechao Xing , Ruichao Shen , Brett Granger , Jing He , Jiang Long , Guoqiang Wang
- Applicant: Enanta Pharmaceuticals, Inc.
- Applicant Address: US MA Watertown
- Assignee: ENANTA PHARMACEUTICALS, INC.
- Current Assignee: ENANTA PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore, Esq.
- Main IPC: A61K31/42
- IPC: A61K31/42 ; C07D413/12 ; C07D261/08
Abstract:
The present invention provides compounds of Formula I: pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.
Public/Granted literature
- US20170334893A1 Isoxazole Analogs as FXR Agonists and Methods of Use Thereof Public/Granted day:2017-11-23
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