- 专利标题： Deuterated bile acids
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申请号： US15651721申请日： 2017-07-17
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公开(公告)号： US10144758B2公开(公告)日： 2018-12-04
- 发明人: Michael D Finch , Walter Low , Clifford Steer , Cyrus B. Munshi , Cecilia M. P. Rodrigues , Susana Dias Lucas de Oliveira
- 申请人： Metselex, Inc.
- 申请人地址： US MN Minneapolis
- 专利权人： Metselex, Inc.
- 当前专利权人： Metselex, Inc.
- 当前专利权人地址： US MN Minneapolis
- 代理机构： Schwegman Lundberg & Woessner, P.A.
- 主分类号： C07J9/00
- IPC分类号： C07J9/00 ; C07J41/00 ; A61K31/575
摘要：
This disclosure relates to deuterated bile acid compositions. A deuterated compound is selected from the bile acids such as ursodeoxycholic acid (UDCA) and tauroursodeoxycholic acid (TUDCA), and their derivatives, analogs and salts. At least one of the hydrogen atoms in the compound is replaced with deuterium. Also disclosed are pharmaceutical compositions and methods of using the deuterated bile acids.
公开/授权文献
- US20180030084A1 DEUTERATED BILE ACIDS 公开/授权日：2018-02-01
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