A method and system for displaying images captured by an in vivo imaging device are disclosed. Embodiments according to the present invention display image sequence data in a first display area. When a first bookmarked image with annotation information is displayed in the first display area, a first thumbnail image in a second display area corresponding to the first bookmarked image is replaced to indicate an occurring correspondence between the first bookmarked image and the first thumbnail image corresponding to the first bookmarked image being displayed. In one embodiment, the method further comprises displaying the first thumbnail image in the second display area when one other image of the image sequence data is displayed in the first display area after the first bookmarked image is displayed.