A vehicular infotainment system, a vehicle and a method of controlling interaction between a vehicle driver and an infotainment system. A multimedia device, a human-machine interface and sensors are used to collect in-vehicle driver characteristic data and extra-vehicle driving conditions. The system additionally includes—or is otherwise coupled to—a computer to convert one or both of traffic pattern data and vehicular positional data into a driver elevated cognitive load profile. In addition, the computer converts the driver characteristic data into a driver mood profile. The system can process these profiles to selectively adjust one or both of the amount of time needed to accept audio commands from a driver and the amount of time needed to provide an audio response to the driver in situations where the system determines the presence of at least one of the elevated cognitive load and a driver mood.