A system for use with a tablet computer includes a host electronic board configured to connect the tablet computer to a plurality of peripheral devices. An enclosure is configured to enclose the host electronic board and the tablet computer in an interior space of the enclosure. The enclosure includes a first part and a second part, which are moveable relative to one another between an open position for adding and removing the tablet computer from the enclosure and a closed position. The enclosure is configured so the interior space of the enclosure is substantially inaccessible from outside the enclosure in the closed position. The system includes a lock on the enclosure. The lock is configured to selectively convert from an unlocked configuration in which the first and second parts of the enclosure can be moved to the open position and a locked configuration in which the first and second parts of the enclosure cannot be non-destructively moved from the closed position to the open position.