Invention Grant
- Patent Title: Methods for monitoring ELOVL2, KLF14 and PENK gene expression following treatment with vitamin C
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Application No.: US15610407Application Date: 2017-05-31
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Publication No.: US10202650B2Publication Date: 2019-02-12
- Inventor: Kang Zhang , Rui Hou , Lianghong Zheng
- Applicant: The Regents of the University of California , YouHealth Biotech, Limited
- Applicant Address: KY Grand Cayman US CA Oakland
- Assignee: YOUHEALTH BIOTECH, LIMITED,THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: YOUHEALTH BIOTECH, LIMITED,THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: KY Grand Cayman US CA Oakland
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C12Q1/6876
- IPC: C12Q1/6876 ; C12Q1/6883 ; G01N33/574

Abstract:
Disclosed herein are methods of increasing the expression rate of epigenetic markers such as ELOVL2, KLF14, and PENK with administration of a therapeutic agent (e.g., vitamin C or its derivatives, analogs, metabolites, prodrugs, or pharmaceutically acceptable salts thereof). Also described herein are methods of modulating the methylation pattern of epigenetic markers such as ELOVL2, KLF14, and PENK with administration of a therapeutic agent (e.g., vitamin C or its derivatives, analogs, metabolites, prodrugs, or pharmaceutically acceptable salts thereof).
Public/Granted literature
- US20170342496A1 METHODS FOR EVALUATING, MONITORING, AND MODULATING AGING PROCESS Public/Granted day:2017-11-30
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