System and methods for estimating a state if a fuse are presented. In some embodiments, the disclosed systems and methods may be utilized in connection with estimating a state of a fuse associated with a manual service disconnect associated with an energy storage system included in a vehicle. Consistent with embodiments disclosed herein, a current event counting-based method utilizing one or more weighted time data buckets associated with various current levels may be used in connection with estimating MSD fuse life. In some embodiments, a MSD fuse end-of-service life signal may be triggered when a total time associated in the weighted time data buckets exceed a threshold value.