The present disclosure relates to a pixel circuit, a display substrate, a display device, and a method for driving the display substrate. The pixel circuit includes an offset control unit, which is connected between a reset control terminal and a first end of an electroluminescent unit and is configured to be turned on in a case that a reset control signal is applied to the reset control terminal, and to set a voltage of the first end of the electroluminescent unit to be a voltage of the reset control signal.