A method of manufacturing a printing blanket without wrinkles in a sheet is provided, the printing blanket including an elastic body and a sheet bonded to a surface thereof, the method being configured to press a surface of the sheet against a surface to be printed, to perform printing, and including: fixing the sheet at a periphery of a region of the sheet to be bonded to the elastic body; mounting the elastic body to oppose a bonding surface of the elastic body to a bonding surface of the fixed sheet; applying an adhesive to at least one of the bonding surface of the sheet or the bonding surface of the elastic body; and pressing the bonding surface of the sheet and the bonding surface of the elastic body against each other to bring the sheet into close contact with the elastic body through intermediation of the adhesive while stretching the sheet along the surface of the elastic body.