- 专利标题： Extracellular hyaluronidase from Streptomyces koganeiensis
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申请号： US15226593申请日： 2016-08-02
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公开(公告)号： US10208300B2公开(公告)日： 2019-02-19
- 发明人: Luciano Messina , Susanna Vaccaro , Salvatore Caruso , Giovanni Gennari
- 申请人： FIDIA FARMACEUTICI S.P.A.
- 申请人地址： IT Abano Terme (PD)
- 专利权人： FIDIA FARMACEUTICI S.P.A.
- 当前专利权人： FIDIA FARMACEUTICI S.P.A.
- 当前专利权人地址： IT Abano Terme (PD)
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： ITMI2009A0831 20090514
- 主分类号： C12N13/00
- IPC分类号： C12N13/00 ; C12N9/26 ; C07K14/315 ; C07K14/435 ; A61K38/47 ; A61K39/35 ; A61K45/06 ; A61K38/00
摘要：
A process for preparing Streptomyces koganeiensis ATCC 31394 hyaluronidase by obtaining hyaluronidase having molecular weight of 21.6 kDalton, which has hyaluronidase activity and stability markedly higher than those of the hyaluronidase obtained from such microorganism to date.
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