A color filter substrate, a display panel and a display device are provided. The color filter substrate includes a plurality of edge pixels. Each edge pixel includes a plurality of subpixels. Each subpixel is divided by the border line into a display portion at the display region and a non-display portion beyond the display region. The non-display portion is covered with a light-shielding layer. The plurality of subpixels includes a standard subpixel and a plurality of to-be-adjusted subpixels. For each to-be-adjusted subpixel, an additional light-shielding layer is provided at the display portion of the to-be-adjusted subpixel, or the light-shielding layer covering the non-display portion of the to-be-adjusted subpixel is provided with at least one aperture.