- 专利标题: Hot melt fragmentation extruder and process
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申请号: US15920133申请日: 2018-03-13
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公开(公告)号: US10213948B2公开(公告)日: 2019-02-26
- 发明人: Babu Padmanabhan , Suneela Prodduturi , Himadri Sen
- 申请人: SteerLife India Private Limited
- 申请人地址: IN Bengaluru
- 专利权人: Steerlife India Private Limited
- 当前专利权人: Steerlife India Private Limited
- 当前专利权人地址: IN Bengaluru
- 代理机构: Klarquist Sparkman, LLP
- 优先权: IN2295/CHE/2013 20130527
- 主分类号: A61K9/16
- IPC分类号: A61K9/16 ; A61K9/20 ; B29C47/00 ; B29C47/40 ; B29C47/60 ; B29C47/80 ; B29K91/00 ; B29K105/00
摘要:
A co-rotating twin screw extruder for forming fragments is disclosed. The extruder comprises of an intake zone for receiving one or more excipient(s) suitable for oral dosage or one or more excipient(s) suitable for oral dosage along with one or more active pharmaceutical ingredient, a melt zone for softening at least one excipient to form a viscous mass or melt and a fragmenting zone for fragmenting and cooling the viscous mass into cooled fragments and an extruder outlet for recovering the cooled fragments from the extruder.
公开/授权文献
- US20180200938A1 HOT MELT FRAGMENTATION EXTRUDER AND PROCESS 公开/授权日:2018-07-19