- 专利标题: Substituted pyrazoles as inhibitors of fibroblast growth factor receptor
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申请号: US15741639申请日: 2016-08-19
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公开(公告)号: US10214515B2公开(公告)日: 2019-02-26
- 发明人: Lei Chen , Dongliang Guan , Hua Bai , Xing Yan , Shuai Miao , Songsong Zhu
- 申请人: Zhejiang Hisun Pharmaceutical Co., Ltd.
- 申请人地址: CN
- 专利权人: Zhejiang Hisun Pharmaceutical Co., Ltd.
- 当前专利权人: Zhejiang Hisun Pharmaceutical Co., Ltd.
- 当前专利权人地址: CN
- 代理机构: Lerner, David, Littenberg, Krumholz & Mentlik, LLP
- 优先权: CN201510514203 20150820
- 国际申请: PCT/CN2016/096088 WO 20160819
- 国际公布: WO2017/028816 WO 20170223
- 主分类号: A61K31/4155
- IPC分类号: A61K31/4155 ; C07D231/38 ; C07D403/14 ; A61K31/4184 ; A61P35/00 ; C07D233/06 ; C07D233/28 ; C07D233/46 ; C07D233/48 ; C07D401/14
摘要:
An indole derivative as expressed by Formula (I), a preparation method thereof, a pharmaceutical salt, and use thereof as a therapeutic agent, especially as a FGFR inhibitor. Each substituent in Formula (I) has identical definition as specified in the specification.