- Patent Title: Micelle containing epirubicin-complexed block copolymer and anti-cancer agent, and pharmaceutical composition containing said micelle applicable to treatment of cancer, resistant cancer or metastatic cancer
-
Application No.: US15503370Application Date: 2015-08-11
-
Publication No.: US10220026B2Publication Date: 2019-03-05
- Inventor: Hiroaki Kinoh , Kazunori Kataoka , Horacio Cabral , Yutaka Miura , Shigeto Fukushima , Nobuhiro Nishiyama , Tsukasa Chida
- Applicant: The University of Tokyo , Tokyo Institute of Technology
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: THE UNIVERSITY OF TOKYO,TOKYO INSTITUTE OF TECHNOLOGY
- Current Assignee: THE UNIVERSITY OF TOKYO,TOKYO INSTITUTE OF TECHNOLOGY
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Priority: JP2014-163989 20140811
- International Application: PCT/JP2015/072797 WO 20150811
- International Announcement: WO2016/024595 WO 20160218
- Main IPC: A61K31/4402
- IPC: A61K31/4402 ; A61K31/4545 ; A61K31/475 ; A61K31/553 ; A61K31/704 ; A61K31/4375 ; A61K47/48 ; A61K9/00 ; A61K45/06 ; A61K47/60 ; A61K47/59 ; A61K47/69
Abstract:
The problem addressed by the present invention is to develop a pharmaceutical having therapeutic efficacy against epirubicin-resistant tumors. The present invention provides a micelle having an anti-cancer agent disposed inside the core of the micelle formed by an epirubicin-conjugated copolymer.
Public/Granted literature
Information query
IPC分类:
