- 专利标题： (Thio, oxo, and seleno) semicarbazone complexes with zinc and their use for treating cancer
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申请号： US15545966申请日： 2016-01-27
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公开(公告)号： US10221133B2公开(公告)日： 2019-03-05
- 发明人: David J. Augeri , Anthony F. Bencivenga , Adam Blanden , Darren R. Carpizo , John A. Gilleran , Spencer David Kimball , Stewart N. Loh , Xin Yu
- 申请人： RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY , THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
- 申请人地址： US NJ New Brunswick US NY Syracuse
- 专利权人： Rutgers, The State University of New Jersey,The Research Foundation for the State University of New York
- 当前专利权人： Rutgers, The State University of New Jersey,The Research Foundation for the State University of New York
- 当前专利权人地址： US NJ New Brunswick US NY Syracuse
- 代理机构： Viksnins Harris Padys Malen LLP
- 国际申请： PCT/US2016/015183 WO 20160127
- 国际公布： WO2016/123246 WO 20160804
- 主分类号： A61K31/175
- IPC分类号： A61K31/175 ; A61K31/315 ; A61K31/397 ; C07D205/04 ; C07D213/53 ; C07D401/12 ; C07C281/08 ; C07C337/08
摘要：
The invention provides organic complexes of Zn2+ of formula (I) that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.
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