A display device with an integrated touch screen and a method of driving the same are provided. The display device includes a panel configured to operate in a first display operation period, a first touch operation period, a second display operation period, and a second touch operation period, and include a touch electrode overlapping a plurality of gate lines and a plurality of data lines, and a gate driver configured to sequentially apply a gate-on voltage to an odd-numbered gate line among the plurality of gate lines during two horizontal periods in the first display operation period, and in the second display operation period, sequentially apply the gate-on voltage to an even-numbered gate line among the plurality of gate lines during two horizontal periods.