- 专利标题： Fused tricyclic heterocyclic compounds useful for treating HIV infection
-
申请号： US15575433申请日： 2016-05-20
-
公开(公告)号： US10233193B2公开(公告)日： 2019-03-19
- 发明人: Tao Yu , Thomas H. Graham , Sherman T. Waddell , John A. McCauley , Andrew W. Stamford , John M. Sanders , Lihong Hu , Jiaqiang Cai , Lianyun Zhao
- 申请人： MERCK SHARP & DOHME CORP. , Tao Yu , Thomas H. Graham , Sherman T. Waddell , John A. McCauley , Andrew W. Stamford , John M. Sanders , Lihong Hu , Jiaqiang Cai , Lianyun Zhao
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Nicole M. Beeler; John C. Todaro
- 优先权： WOPCT/CN2015/079730 20150525
- 国际申请： PCT/US2016/033414 WO 20160520
- 国际公布： WO2016/191239 WO 20161201
- 主分类号： A61K31/4375
- IPC分类号： A61K31/4375 ; C07D491/147 ; A61K31/4355 ; A61K31/437 ; C07D471/14 ; A61K31/427 ; A61K31/4402 ; A61K31/505 ; A61K31/513 ; A61K31/52 ; A61K31/635 ; A61K31/675 ; A61P31/18
摘要：
The present invention relates to Fused Tricyclic Heterocycle Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, Y, m, R1, R2, R3, R3, R3, R4, R5 and R9 are as defined herein. The present invention also relates to compositions comprising at least one Fused Tricyclic Heterocycle Derivative, and methods of using the Fused Tricyclic Heterocycle Derivatives for treating or preventing HIV infection in a subject.