Methods and apparatus for distribution and execution of instructions in a distributed computing environment are disclosed. An example method includes accessing, by executing a first instruction with a processor implementing a management agent within a deployment environment, an indication of a second instruction to be executed, the indication of the second instruction to be executed provided by a management endpoint within the deployment environment. A package supporting execution of the instruction is requested from the management endpoint. A component of the package is loaded into a command cache. The component of the package includes the second instruction to be executed. The command cache is implemented by a plug in framework. The second instruction is executed from the command cache. A result of the execution of the second instruction is collected. The result of the execution of the second instruction is transmitted to the management endpoint.