Invention Grant
- Patent Title: Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts
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Application No.: US15990590Application Date: 2018-05-26
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Publication No.: US10238645B2Publication Date: 2019-03-26
- Inventor: Michael T. Nordsiek , Jefferson J. Gregory
- Applicant: Medicis Pharmaceutical Corporation
- Applicant Address: US NJ Bridgewater
- Assignee: Medicis Pharmaceutical Corporation
- Current Assignee: Medicis Pharmaceutical Corporation
- Current Assignee Address: US NJ Bridgewater
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K9/06 ; A61K31/44 ; A61K47/10 ; A61K47/12 ; A61K31/4745

Abstract:
Pharmaceutical formulations and methods for the topical or transdermal delivery of 1isobutyl-1H-imidazo[4,5-c]-quinolin-4-amine or 1-(2-methylpropyl)-1H-imidazo[4,5 c]quinolin-4-amine, i.e., imiquimod, to treat genital/perianal warts with shorter durations of therapy than currently prescribed for the commercially available for Aldara® 5% imiquimod cream, as now approved by the U.S. Food & Drug Administration (“FDA”), are disclosed and described. More specifically, lower dosage strength imiquimod formulations to deliver an efficacious dose of imiquimod for treating genital/perianal warts with an acceptable safety profile and dosing regimens that are shorter and more convenient for patient use than the dosing regimen currently approved by the U.S. Food & Drug Administration (“FDA”) for Aldara® 5% imiquimod cream to treat genital/perianal warts are also disclosed and described.
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Information query