- 专利标题： Treatment of paroxysmal nocturnal hemoglobinuria, hemolytic anemias and disease states involving intravascular and extravascular hemolysis
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申请号： US13505150申请日： 2010-11-05
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公开(公告)号： US10239937B2公开(公告)日： 2019-03-26
- 发明人: V. Michael Holers , Antonio M. Risitano
- 申请人： V. Michael Holers , Antonio M. Risitano
- 申请人地址： US MA Boston
- 专利权人： Alexion Pharmaceuticals, Inc.
- 当前专利权人： Alexion Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Boston
- 代理机构： Clark & Elbing LLP
- 国际申请： PCT/US2010/055745 WO 20101105
- 国际公布： WO2011/057158 WO 20110512
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; C07K14/47 ; C07K14/705 ; A61K38/17
摘要：
Methods for treating subjects having complement-mediated hemolytic disorders, such as paroxysmal nocturnal hemoglobinuria (PNH) and other hemolytic anemias, the method comprising administering an effective amount of a composition that inhibits the activity of the complement alternative pathway.
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