Invention Grant
- Patent Title: Method for the production of protein complexes and vaccine compositions comprising the same
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Application No.: US14006586Application Date: 2012-03-23
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Publication No.: US10240179B2Publication Date: 2019-03-26
- Inventor: Camilo Colaco , Ian McEntee
- Applicant: Camilo Colaco , Ian McEntee
- Applicant Address: GB Cambridge
- Assignee: Immunobiology Limited
- Current Assignee: Immunobiology Limited
- Current Assignee Address: GB Cambridge
- Agency: Winstead PC
- Priority: GB1104897.2 20110323
- International Application: PCT/GB2012/050650 WO 20120323
- International Announcement: WO2012/127248 WO 20120927
- Main IPC: C12P21/00
- IPC: C12P21/00 ; A61K39/00 ; A61K38/17 ; A61K39/04 ; A61K39/08 ; A61K39/09 ; A61K39/095
Abstract:
The present invention relates to methods for the production of heat shock protein complexes for use in vaccine compositions. In particular, there is provided a method for increasing the level and immunogenicity of heat shock protein complexes produced in cells by subjecting the cells to specific stress inducing stimuli. The invention further extends to the use of heat shock protein complexes produced according to the methods of the invention in the preparation of vaccine compositions for the prevention and treatment of infectious diseases and cancerous conditions.
Public/Granted literature
- US20140017274A1 METHOD FOR THE PRODUCTION OF PROTEIN COMPLEXES AND VACCINE COMPOSITIONS COMPRISING THE SAME Public/Granted day:2014-01-16
Information query
