Systems and methods for secure resource access and network communication are provided. A plurality of policies are received on a client device, each policy comprising a respective resource and a respective permission for a respective action that can be performed by a user of the client device in regards to the resource. A first application, which is configured to store data in an encrypted repository on the client device, receives a request to open a resource. The first application determines that one of the policies prohibits access by the resource to the encrypted repository and, based thereon, selects a different second application to open the resource that does not have access to the encrypted repository. The second application then opens the resource.