A patient interface system for delivering a flow of breathable gas to a patient includes a patient interface structure configured to sealingly engage the face of the patient and a retaining element configured for application to the patient. The retaining element is configured to support the patient interface structure in sealing engagement with the face of the patient. The retaining element includes an adhesive and/or at least one strap. In addition, the patient interface structure is configured to be released from and re-engaged with the retaining element for re-positioning of the patient interface structure relative to the patient's face in a plurality of positions while the retaining element remains supported by the patient.